彭练慈,博士,毕业于荷兰乌特勒支大学(Utrecht University),重庆市第四类人才(获重庆英才AIII服务卡)。
系所:预防兽医学
职称:副教授
电子邮箱:penglianci@swu.edu.cn
讲授课程:兽医免疫学
研究方向
主要从事病原感染诱导宿主免疫应答的机制研究,聚焦于抗菌肽抗感染及免疫调节机制的研究。承担的课程有兽医免疫学。
工作经历
2020.10—至今,西南大学,动物医学院,讲师。
教育背景:
2016.11—2020.07,荷兰乌特勒支大学(Utrecht University),兽医学,博士;
2012.09—2015.06,四川农业大学,基础兽医学,硕士;
2009.09—2013.06,四川农业大学,动物医学,本科;
科研项目:
1. 抗菌肽CATH-2调控宿主天然免疫应答的分子机制研究,西南大学博士基金/引进人才计划项目,SWU120057,2021.05.01-2023.04.30,主持;
2. 鸡源抗菌肽CATH-2抑制禽致病性大肠杆菌诱导炎症小体活化的分子机制研究,国家自然科学基金青年项目,32102684,2022.01.01-2024.12.31,主持;
3. 鸡源抗菌肽CATH-2抑制金黄色葡萄球菌感染中NLRP3炎症小体激活的分子机制研究,重庆市自然科学基金面上项目,cstc2021jcyj-msxm2218,2021.07.01-2023.06.23,主持。
代表性论文:
(1)Lianci Peng; Yi Lu; Hongliang Tian; Kaixiang Jia; Qi Tao; Gang Li; Chao Wan; Chao Ye; Edwin J.A. Veldhuizen; Hongwei Chen; Rendong Fang; Chicken cathelicidin-2 promotes IL-1β secretion via the NLRP3 inflammasome pathway and serine proteases activity in LPS-primed murine neutrophils.Developmental and Comparative Immunology, 2022.
(2) Fengqing Hou#;Lianci Peng#; Jiali Jiang; Tingting Chen; Dongyi Xu; Qingyuan Huang; Chao Ye; Yuanyi Peng; Dong-Liang Hu; Rendong Fang; ATP Facilitates Staphylococcal Enterotoxin O Induced Neutrophil IL-1β Secretion via NLRP3 Inflammasome Dependent Pathways,Frontiers in Immunology, 2021, 12: 649235.(#共同第一)
(3)LianciPeng#;JialiJiang#; Tingting Chen; Dongyi Xu; Fengqing Hou; Qingyuan Huang; Yuanyi Peng; Chao Ye; Dong-Liang Hu *; Rendong Fang *; Toxic Shock Syndrome Toxin 1 Induces Immune Response via the Activation of NLRP3 Inflammasome,Toxins, 2021, 13(1):68.
(4)Lianci Peng; Maaike R. Scheenstra; Roel M. van Harten; Henk P. Haagsman; Edwin J.A. Veldhuizen*; The immunomodulatory effect of chicken cathelicidin-B1 on chicken macrophages, Veterinary Research, 2020, 51(1):122.
(5)Lianci Peng; Wenjuan Du; Melanie D. Balhuizen; Henk P. Haagsman; Cornelis A.M. de Haan; Edwin J.A. Veldhuizen*; Antiviral activity of chicken cathelicidin B1 against influenza A virus, Frontiers in Microbiology, 2020, 11: 426.
(6)Lianci Peng; Robin H.G.A van den Biggelaar; Christine A. Jansen; Henk P. Haagsman; Edwin J.A. Veldhuizen*; A method to differentiate chicken monocytes into macrophages with proinflammatory properties,Immunobiology,2020,225(6):152004.
(7)Lianci Peng; Mieke G.R. Matthijs; Henk P. Haagsman; Edwin J.A. Veldhuizen*; Avian pathogenic Escherichia coli-induced activation of chicken macrophage HD11 cells, Developmental and Comparative Immunology, 2018, 87: 75-83.